EFEKTIVITAS EKSTRAK DAUN KIPAHIT (Tithonia diversifolia) SEBAGAI ALTERNATIF REPELEN ALAMI DAN LARVASIDA UNTUK Aedes aegypti

Abstract

Dengue Hemorrhagic Fever (DHF) is a tropical disease that remains a public health challenge in Indonesia. Control of the Aedes aegypti mosquito vector must be carried out effectively and environmentally friendly. This study aims to evaluate the effectiveness of kipahit leaf extract (Tithonia diversifolia) as a repellent against adult mosquitoes and a larvicide against third-instar Aedes aegypti larvae. In this study, five concentration variations were used in each test: 0 mL, 12.5 mL, 25 mL, 37.5 mL, 50 mL (for the repellent) and 0 mL, 4.5 mL, 9 mL, 16 mL, and 28 mL (for the larvicide). The repellent test was conducted using mice as the experimental animals, while the larvicide was tested on third-instar mosquito larvae. The results showed that the highest protective effect (55.5%) was achieved at a concentration of 50 mL, while the highest larval mortality rate (75%) occurred at a concentration of 28 mL. The LC₅₀ value for the kipahit leaf extract was recorded at 2.61%. Thus, the kipahit leaf extract demonstrated greater potential as a larvicide compared to its function as a repellent.